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KMID : 0882420140860020169
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Korean Journal of Medicine
2014 Volume.86 No. 2 p.169 ~ p.178
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Clinical Impact of High Triglycerides and Central Obesity in Patients with Acute Myocardial Infarction who Underwent Percutaneous Coronary Intervention
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Han Soo-Gyoung
Jeong Myung-Ho
Rhee Jung-Ae
Choi Jin-Su
Lee Ki-Hong
Park Keun-Ho
Sim Doo-Sun
Hong Young-Joon
Kim Ju-Han
Ahn Young-Keun
Cho Jeong-Gwan
Park Jong-Chun
Kang Jung-Chaee
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Abstract
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Background/Aims: Dyslipidemia and obesity are risk factors for the development of acute myocardial infarction (AMI) that affect the clinical outcomes in patients.
Methods: We analyzed 2,751 consecutive AMI patients who underwent percutaneous coronary intervention (PCI) (mean age, 63.7 ± 12.1 years). The patients were divided into four groups based on serum triglyceride levels and central obesity [Group Ia: triglycerides < 200 mg/dL and (-) central obesity; Group Ib: triglyceride < 200 mg/dL and (+) central obesity; Group IIa: triglyceride ≥ 200 mg/dL and (-) central obesity; Group IIb: triglyceride ≥ 200 mg/dL and (+) central obesity]. In-hospital outcome was defined as in-hospital mortality and complications. One-year clinical outcome was compared and defined as the composite of 1-year major adverse cardiac events (MACE), including death, recurrent MI, and target vessel revascularization.
Results: Total MACE developed in 502 patients (18.2%), while 303 patients (11.0%) died prior to the 1-year follow-up visit. In-hospital complications and in-hospital mortality were not different among the four groups. One-year clinical outcomes based on triglyceride levels (Group I vs. Group II) were not different. In addition, there were no differences in clinical outcomes in patients with a triglyceride level < 200 mg/dL, regardless of central obesity. One-year MACE rates were not significantly different among the four groups.
Conclusions: There was no significant difference in the 1-year MACE rate based on the triglyceride level and presence of central obesity in patients with AMI who underwent PCI.
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KEYWORD
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Acute myocardial infarction, Obesity, Triglyceride, Mortality
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